Manchester United have been drawn against Granada in the Europa League quarter-finals, while Arsenal will play Rangers’ conquerors, Slavia Prague.
United could face Ajax or Roma in the last four, while for Arsenal, a potential meeting with Dinamo Zagreb or Villarreal is on the cards.
After Rangers and Tottenham exited the tournament on Thursday night, the draw means the two remaining British sides, United and Arsenal, could only meet in the final.
United overcame a tricky tie against Milan to advance 2-1 on aggregate thanks to Paul Pogba’s winner in Italy on Thursday night.
Granada are playing in Europe for the first time and their last-eight tie against Manchester United will be their first meeting with English opposition.
The Red Devils are one of only two previous winners left in the competition along with 1992 champions Ajax, who United beat in the 2017 final.
Arsenal were involved in the last all-English Europa League final against Chelsea in 2019, with the Blues winning 4-1 in Baku.
Slavia Prague meanwhile have been drawn against a British club for the third time this season having beaten Leicester and Rangers in the previous rounds.
Croatian champions Dinamo Zagreb reached this stage after a remarkable 3-2 aggregate victory against Tottenham.
The two-legged quarter-final ties will be played on 8 and 15 April.
The semi-finals are scheduled for 29 April and 6 May.
*Europa League quarter-final draw:*
Granada v Manchester United
Arsenal v Slavia Prague
Ajax v Roma
Dinamo Zagreb v Villarreal
*Europa League semi-final draw:*
Granada/Manchester United v Ajax/Roma
Dinamo Zagreb/Villarreal v Arsenal/Slavia Prague